Which of the following is not used to treat endometriosis?

Which of the following is not used to treat endometriosis?

• A. Trazodone
• B. Leuprolide
• C. Nafarelin acetate
• D. Diclofenac

Answer: (A)

Endometriosis treatment targets estrogen-driven growth and pain. GnRH agonists like leuprolide and nafarelin acetate suppress ovarian estrogen production, causing atrophy of endometriotic implants. Diclofenac, a nonsteroidal anti-inflammatory drug, provides symptomatic relief from pelvic pain and dysmenorrhea but does not address the underlying disease process. Trazodone is an antidepressant used for mood and sleep symptoms; it does not affect endometrial implants or the hormonal or inflammatory pathways driving endometriosis, so it isn’t used to treat the condition.

Endometriosis treatment targets estrogen-driven growth and pain. GnRH agonists like leuprolide and nafarelin acetate suppress ovarian estrogen production, causing atrophy of endometriotic implants. Diclofenac, a nonsteroidal anti-inflammatory drug, provides symptomatic relief from pelvic pain and dysmenorrhea but does not address the underlying disease process. Trazodone is an antidepressant used for mood and sleep symptoms; it does not affect endometrial implants or the hormonal or inflammatory pathways driving endometriosis, so it isn’t used to treat the condition.